Highlights
Engineering Protein A to Z for VH3 antibody purification
Antibody purification is often taken for granted. It’s an essential step in isolating desirable antibodies for research and drug development and a standard part of antibody production at the Institute…
Inside the IPI pipeline
Of the tools underpinning biomedical research, antibodies are among the most impactful. Their ability to recognize and attach to biomolecules has powered fundamental discoveries, diagnostic methods and treatments for diseases,…
Bioscience leader Ken Fasman to steer IPI as new president and CEO
The walls of Ken Fasman’s ninth-floor office are still bare. But the new president and CEO at the Institute for Protein Innovation (IPI) has plans that could fill the room.…
Dream come true: Zehra Sayers builds structural biology for the next generations
Zehra Sayers always dreamed of finding precise answers to life’s core questions. A professor and former president of Turkey’s Sabancı University — and one of the BBC’s most influential women…
With a modern take on a family legacy, Stephen Blacklow joins IPI to push bioscience forward
Stephen Blacklow has biomedical curiosity in his genes. As the newest Board of Directors member at the Institute for Protein Innovation (IPI) and the Gustavus Adolphus Pfeiffer Professor and chair…
IPI co-founder Timothy Springer wins Lasker Award, highlighting key chapter in biology
Scientist, entrepreneur and philanthropist Timothy Springer is one of three scientists to win the 2022 Albert Lasker Award for Basic Medical Research, widely regarded as America’s top biomedical research prize.…
Integrins: Explained
More than 600 million years ago, out of the depths of the metazoa, a protein family emerged — one that would persist through evolution and come to shape life today.…
Six new scientists bring expertise, tenacity to IPI team
Since early 2021, the Institute for Protein Innovation (IPI) has hired six scientists, bringing specialties in G protein-coupled receptors, post-translational modifications, protein expression and more to help IPI’s antibody platform…
New federation aims to transform biology with protein tools spanning proteome by 2035
An ambitious protein moonshot is gaining momentum to develop and widely share tools that will land us understanding of the complete human proteome. In 2003, biology was all about the…
From Rob Meijers, interim executive director: In 2021, IPI explored ‘new frontiers’ in antigen and antibody discovery
As the world struggled to live in and through a seeming “forever pandemic,” 2021 was a year that demanded global resilience. The potency of delta followed by fast spread of…
Uncovering the secrets of mechanotransduction, one integrin receptor at a time
For the body to function, cells must decide. Embryonic cells elect to reproduce and shape into budding limbs. Immune cells choose to leave the bloodstream en route to an infection…
New federation aims to transform biology with protein tools spanning proteome by 2035
An ambitious protein moonshot is gaining momentum to develop and widely share tools that will land us understanding of the complete human proteome. In 2003, biology was all about the…
From Rob Meijers, interim executive director: In 2021, IPI explored ‘new frontiers’ in antigen and antibody discovery
As the world struggled to live in and through a seeming “forever pandemic,” 2021 was a year that demanded global resilience. The potency of delta followed by fast spread of…
A mystery launched a decade-long quest, leading to a novel cause of bone marrow failure
Twelve years ago, after a routine check-up of a newborn, a medical resident inadvertently ordered a nonroutine blood test. The results came as a surprise: The infant had virtually no…
Ubiquitous yet less severe, did omicron sacrifice virulence to evade immunity?
According to conventional wisdom, a SARS-CoV-2 variant becomes more infectious when it mutates to better bind and invade host cells. But a new study on omicron, which carries quadruple the…
Super toxin linked to food poisoning could bind to all human cells, cause other illnesses
Grape-like clusters of the bacterium Staphylococcus aureus might look harmless under a microscope. But they’re capable of causing great mayhem. Think food poisoning, a result of S. aureus’ most common…
Antibodies are going from biology’s workhorses to precision tools, a boon for reliable research
Roughly a decade ago, biologists conducting high-stakes experiments noticed a pattern: Many findings couldn’t be replicated in other labs, throwing doubt on data that should have led to treatments for…
To try to hone COVID-19 vaccines beyond variants, scientists can zoom in on mutations
Concern that omicron, the latest coronavirus variant, could be poised to overtake delta, which swept the globe in roughly two months since it was first identified, has steadily grown. But…
The German translation for opioid
An opioid crisis in the US is not news. Indeed, the Centers for Disease Control and Prevention estimate nearly 841,000 people in the US have died in the last two…
Pursuing a ‘diff’erent microbe
The world now understands all too well the peril of coronaviruses. Yet, microbiologists and healthcare professionals also know the dangers of another destructive microbe. Clostridium difficile is a bacterium that…
IPI starts new chapter with game-changing gift: A Q&A with Tim Springer
Big philanthropic gifts can be powerful vehicles of transformation for any young organization. With a history of scientific renown and entrepreneurial success, Institute for Protein Innovation (IPI) cofounder Tim Springer,…
Sophia Ulmer brings creativity and computational prowess to protein engineering
Art and science can seem at odds. But fundamentally, both focus on exploration and the discovery of the unknown. In the Institute for Protein Innovation (IPI) laboratory, Sophia Ulmer mixes…
Chasing a ‘quantum leap’ in cell surface biology: A Q&A with Junichi Takagi
Cell surface receptors are, by and large, the main molecular target for therapeutics. Also known as transmembrane receptors, they’re the targets of more than 60% of drugs today. But scientists…
Bioscience leader Ken Fasman to steer IPI as new president and CEO
The walls of Ken Fasman’s ninth-floor office are still bare. But the new president and CEO at the Institute for Protein Innovation (IPI) has plans that could fill the room.…
Dream come true: Zehra Sayers builds structural biology for the next generations
Zehra Sayers always dreamed of finding precise answers to life’s core questions. A professor and former president of Turkey’s Sabancı University — and one of the BBC’s most influential women…
With a modern take on a family legacy, Stephen Blacklow joins IPI to push bioscience forward
Stephen Blacklow has biomedical curiosity in his genes. As the newest Board of Directors member at the Institute for Protein Innovation (IPI) and the Gustavus Adolphus Pfeiffer Professor and chair…
IPI co-founder Timothy Springer wins Lasker Award, highlighting key chapter in biology
Scientist, entrepreneur and philanthropist Timothy Springer is one of three scientists to win the 2022 Albert Lasker Award for Basic Medical Research, widely regarded as America’s top biomedical research prize.…
Six new scientists bring expertise, tenacity to IPI team
Since early 2021, the Institute for Protein Innovation (IPI) has hired six scientists, bringing specialties in G protein-coupled receptors, post-translational modifications, protein expression and more to help IPI’s antibody platform…
Research, clinical care and community: Eliza Gavin balances three medical strategies as a prospective physician-scientist
Eliza Gavin was always the kid who wondered why. As a middle schooler, she’d look at a piece of crystallized rock candy, hypothesize how it formed and then learn how…
At a workshop where ‘structure meets function,’ a team of scientists polished a breakthrough
Most scientists attend conferences armed with posters and presentations. But in addition to those, protein chemist Jonathan Elegheert came to the 2018 Molecular Neurobiology Workshop with a protein and a pitch.…
Engineering Protein A to Z for VH3 antibody purification
Antibody purification is often taken for granted. It’s an essential step in isolating desirable antibodies for research and drug development and a standard part of antibody production at the Institute…
Inside the IPI pipeline
Of the tools underpinning biomedical research, antibodies are among the most impactful. Their ability to recognize and attach to biomolecules has powered fundamental discoveries, diagnostic methods and treatments for diseases,…
Integrins: Explained
More than 600 million years ago, out of the depths of the metazoa, a protein family emerged — one that would persist through evolution and come to shape life today.…
Harvard professor and entrepreneur Tim Springer donates $210 million to the Institute for Protein Innovation
The gift further positions the emerging nonprofit to transform biomedical research with novel protein tools and expertise BOSTON, March 29, 2023 — The Institute for Protein Innovation (IPI), a nonprofit…
Institute for Protein Innovation welcomes top researchers at first symposium
BOSTON, March 29, 2023 — The Institute for Protein Innovation (IPI) will host IPI Surfacing, a symposium on cell surface receptor biology, on Thursday, June 15, 2023. The free, day-long…
Institute for Protein Innovation welcomes esteemed industry leader Kenneth Fasman, Ph.D. as president and chief executive officer
Boston, November 15, 2022 — The Institute for Protein Innovation (IPI), a nonprofit research organization advancing protein science to accelerate biomedical research and improve human health, today announced the appointment…
AI Proteins secures $18.2 million seed round to pioneer high-throughput platform for advanced miniprotein therapeutics
Company to focus on the rapid development of miniproteins tailor-made for therapeutics, driving down costs and shortening the time required to develop safer, more effective medicines. BOSTON—(BUSINESS WIRE)—AI Proteins, the…
IPI co-founder Timothy Springer wins Lasker Award, highlighting key chapter in biology
Scientist, entrepreneur and philanthropist Timothy Springer is one of three scientists to win the 2022 Albert Lasker Award for Basic Medical Research, widely regarded as America’s top biomedical research prize.…
IPI joins an exciting effort to solve the reproducibility crisis
IPI is thrilled to join YCharOS as a member of its new Industry Advisory Committee. The Canadian company, named from a truncation of Antibody Characterization through Open Science, is launching…
Christopher Bahl selected as a TED Fellow
Institute for Protein Innovation Head of Protein Design to present at TED2019, joining the newest class of 20 global visionaries. BOSTON, Jan. 23, 2019 /PRNewswire/ — Molecular Engineer Chris Bahl…
IPI appoints Wei Yang as director of target discovery and Sharon Klein as director of philanthropy
Boston, June 26, 2018 /PR Newswire/ – Institute for Protein Innovation (IPI), a non-profit research organization focused on empowering research in protein science and developing open-source monoclonal antibodies, announced today…
IPI relocates to Boston’s Longwood Medical and Academic Area
BOSTON, May 21, 2018 /PRNewswire/ — Just one year after launch, IPI has relocated to the Harvard Institutes of Medicine at 4 Blackfan Circle, Boston. The 12,000-square-foot lab space represents a dramatic expansion and…
IPI buys Carterra™ Next-Generation Antibody Characterization LSA™ instrumentation
Carterra™ Inc., an innovative label-free biosensor company, and Institute for Protein Innovation (IPI) announced today that IPI has purchased a Carterra LSA™, a fully automated, label-free, high-throughput monoclonal antibody (mAb)…