Halle Marchese

A woman, wearing eye glasses, a lab coat and gloves, uses a multi-channel pipette at a lab bench.

Bespoke high-throughput approach expedites screening of cell-surface ectodomains

Cell-surface receptors are notoriously tricky to produce and purify; they misfold, aggregate, degrade, and often…

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The image looks down the aisle toward a screen, with a microphone in the middle of the aisle. Either side of the aisle is lined with people sitting in folding chairs watching the presentation.

Panel highlights antibody characterization and validation strategies

Biology’s shortage of high-quality, well-performing and easily accessible antibodies is no breaking news; it’s a…

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A man in a lab coat working at a lab bench filled with bottles.

Youssef Atef AbdelAlim carries protein science lessons to medical school

For IPI research associate Youssef Atef AbdelAlim, science is synonymous with patient care. He’s run…

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A man in a lab coat and safety glasses adds a plate of antibody samples to a robot in a lab. A group of three scientists stand in a line, looking at the machine.

Innovation comes naturally to IPI’s director of automation Curtis Walton

When Curtis Walton was young, he’d disassemble household items, diligently learning about their inner mechanisms…

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Illustration of an epitope tag antibody recognizing the epitope tag sequence at a N- or C-terminus.

Epitope tags: Explained

IPI epitope tag antibodies, delivered via an open science model, aim to increase access, cut…

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Rob Meijers pictured in an IPI conefernce room, wearing a button-up shirt and laughing. Laptops are shown in the foreground.

IPI’s community-centered approach to antibody discovery: A Q&A with Rob Meijers

This spring, the Institute for Protein Innovation (IPI) dispatched a collection of antibodies targeting members…

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Debora Marks at IPI: Generative models for prediction and design

Debora Marks gave a seminar at IPI on March 21, 2024. She spoke about her…

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The 3D structure of Sonic Hedgehog.

Cell signaling, Sonic Hedgehog and Hemingway’s cats: A Q&A with Adrian Salic

In 1980, the famous geneticists Christiane Nüsslein-Volhard and Eric Wieschaus were mapping embryonic mutations in…

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Zebrafish lit up under microscopy with visible spine and colored spots marking proteins.

IPI antibody helps illuminate the MYCN-mediated tumor microenvironment

If you were diagnosed with aggressive neuroblastoma, you’d most likely be an infant carrying a…

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“A wise man always keeps learning”: Biotech entrepreneur Rusty Williams joins IPI Board

In 1984, Lewis “Rusty” Williams boarded a flight from Boston to San Francisco and took…

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A group of people sit around a conference room table with laptops and water bottles on the tabletop. André Teixeira sits at the head of the table, smiling.

Engineering for efficiency: André Teixeira takes charge of antibody discovery and library design at IPI

It’s a few minutes after noon, and scientists at the Institute for Protein Innovation (IPI)…

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A digital rendering of neurotransmission in the synapse, shown with glowing neurons flowing at a synaptic connection.

Entry points into neuroscience: A Q&A with Thomas Biederer

At the heart of all nervous system functions are the synapses, where signals fly between…

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