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Receptor Engineering

Rob Meijers, Ph.D.

Selected publications

Anjanappa R, Garcia-Alai M, Kopicki JD, Lockhauserbaumer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers RStructures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selectionNature Communications, vol. 11 (1314), 2020.

Meijers R, Smock RG, Zhang Y, Wang JH. Netrin synergizes signaling and adhesion through DCC. Trends in Biochemical Sciences, vol. 45 (1), 2020.

Liu Y, Bhowmick T, Liu Y, Gao X, Mertens HDT, Svergun DI, Xiao J, Zhang Y, Wang J-h, Meijers R. Structural basis for Draxin-modulated axon guidance and fasciculation by Netrin-1 through DCC. Neuron, vol. 97 (6), 2018.

Finci LI, Krüger N, Sun X, Zhang J, Chegkazi M, Wu Y, Schenk G, Mertens HD, Svergun DI, Zhang Y, Wang JH, Meijers R. The crystal structure of Netrin-1 in complex with DCC reveals the bifunctionality of Netrin-1 as a guidance cue. Neuron, vol. 83 (4), 2014.

Boivin S, Kozak S, Meijers R. Optimization of protein purification and characterization using Thermofluor screens. Protein Expression and Purification, vol. 91 (2), 2013.

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