Selected publications
Kahn, R. A., Virk, H., Laflamme, C., Houston, D. W., Polinski, N. K., Meijers, R.1, Levey, A. I., Saper, C. B., Errington, T. M., Turn, R. E., Bandrowski, A., Trimmer, J. S., Rego, M., Freedman, L. P., Ferrara, F., Bradbury, A. R. M., Cable, H., & Longworth, S. (2024). Antibody characterization is critical to enhance reproducibility in biomedical research. eLife, 13, e100211. https://doi.org/10.7554/eLife.100211
Hao, Y., Yan, J., Fraser, C., Jiang, A., Anuganti, M.1, Zhang, R.1, Lloyd, K.1, Jardine, J.1, Coppola, J.1, Meijers, R.1, Li, J., & Springer, T. A.1 (2024). Synthetic integrin antibodies discovered by yeast display reveal αV subunit pairing preferences with β subunits. mAbs, 16(1), 2365891. https://doi.org/10.1080/19420862.2024.2365891 2
Ghosh, A.1, Yang, C.1, Lloyd, K.1, & Meijers, R.1 (2024). High-Throughput Protein Expression Screening of Cell-Surface Protein Ectodomains. Methods in molecular biology (Clifton, N.J.), 2810, 301–316. https://doi.org/10.1007/978-1-0716-3878-1_19
Fram, B., Su, Y., Truebridge, I.1, Riesselman, A. J., Ingraham, J. B., Passera, A., Napier, E., Thadani, N. N., Lim, S., Roberts, K., Kaur, G., Stiffler, M. A., Marks, D. S., Bahl, C. D.1, Khan, A. R., Sander, C., & Gauthier, N. P. (2024). Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nature communications, 15(1), 5141. https://doi.org/10.1038/s41467-024-49119-x
Qin, X., Lam, A., Zhang, X., Sengupta, S., Iorgulescu, J. B., Ni, H., Das, S., Rager, M., Zhou, Z., Zuo, T., Meara, G. K., Floru, A. E., Kemet, C., Veerapaneni, D., Kashy, D., Lin, L., Lloyd, K.1, Kwok, L., Smith, K. S., Nagaraju, R. T., … Meijers, R.1, … Feng, H. (2024). CKLF instigates a “cold” microenvironment to promote MYCN-mediated tumor aggressiveness. Science advances, 10(11), eadh9547. https://doi.org/10.1126/sciadv.adh9547 2
Priest, J. M., Nichols, E. L., Smock, R. G., Hopkins, J. B., Mendoza, J. L., Meijers, R.1, Shen, K., & Özkan, E. (2024). Structural insights into the formation of repulsive netrin guidance complexes. Science advances, 10(7), eadj8083. https://doi.org/10.1126/sciadv.adj8083
Ferrara, F., Fanni, A., Teixeira, A. A. R.1, Molina, E., Leal-Lopes, C., DeAguero, A., D’Angelo, S., Erasmus, M. F., Spector, L., Rodriguez Carnero, L. A., Li, J., Pohl, T. J., Suslov, N., Desrumeaux, K., McMahon, C., Kathuria, S., & Bradbury, A. R. M. (2024). A next-generation Fab library platform directly yielding drug-like antibodies with high affinity, diversity, and developability. mAbs, 16(1), 2394230. https://doi.org/10.1080/19420862.2024.2394230
Woellner-Santos, D., Tahira, A. C., Malvezzi, J. V. M., Mesel, V., Morales-Vicente, D. A., Trentini, M. M., Marques-Neto, L. M., Matos, I. A., Kanno, A. I., Pereira, A. S. A., Teixeira, A. A. R.1, Giordano, R. J., Leite, L. C. C., Pereira, C. A. B., DeMarco, R., Amaral, M. S., & Verjovski-Almeida, S. (2024). Schistosoma mansoni vaccine candidates identified by unbiased phage display screening in self-cured rhesus macaques. NPJ vaccines, 9(1), 5. https://doi.org/10.1038/s41541-023-00803-x
Kibria, M. G., Lavine, C. L., Tang, W., Wang, S., Gao, H., Shi, W., Zhu, H.1, Voyer, J., Rits-Volloch, S., Keerti, Bi, C., Peng, H., Wesemann, D. R., Lu, J., Xie, H., Seaman, M. S., & Chen, B. (2023). Antibody-mediated SARS-CoV-2 entry in cultured cells. EMBO reports, 24(12), e57724. https://doi.org/10.15252/embr.202357724
Leal-Lopes, C., D’Angelo, S., Erasmus, M. F., Teixeira, A. A. R.1, Temples, G., Zhou, J., Bradbury, A. R. M., & Ferrara, F. (2023). High throughput purification of monoclonal recombinant antibodies using a Protein-A coated membrane plate system. New biotechnology, 77, 111–119. https://doi.org/10.1016/j.nbt.2023.08.003
Blanchet, C. E., Round, A., Mertens, H. D. T., Ayyer, K., Graewert, M., Awel, S., Franke, D., Dörner, K., Bajt, S., Bean, R., Custódio, T. F., de Wijn, R., Juncheng, E., Henkel, A., Gruzinov, A., Jeffries, C. M., Kim, Y., Kirkwood, H., Kloos, M., Knoška, J., … Meijers, R.1, … Svergun, D. (2023). Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS). Communications biology, 6(1), 1057. https://doi.org/10.1038/s42003-023-05416-7
Shi, W., Cai, Y., Zhu, H.1, Peng, H., Voyer, J., Rits-Volloch, S., Cao, H., Mayer, M. L., Song, K., Xu, C., Lu, J., Zhang, J., & Chen, B. (2023). Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane. Nature, 619(7969), 403–409. https://doi.org/10.1038/s41586-023-06273-4
Zhang, J., Tang, W., Gao, H., Lavine, C. L., Shi, W., Peng, H., Zhu, H.1, Anand, K.1, Kosikova, M., Kwon, H. J., Tong, P., Gautam, A., Rits-Volloch, S., Wang, S., Mayer, M. L., Wesemann, D. R., Seaman, M. S., Lu, J., Xiao, T., Xie, H., … Chen, B. (2023). Structural and functional characteristics of the SARS-CoV-2 Omicron subvariant BA.2 spike protein. Nature structural & molecular biology, 30(7), 980–990. https://doi.org/10.1038/s41594-023-01023-6
Guédez, G., Loers, G., Jeffries, C. M., Kozak, S., Meijers, R.1, Svergun, D. I., Schachner, M., & Löw, C. (2023). X-ray structure and function of fibronectin domains two and three of the neural cell adhesion molecule L1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 37(3), e22823. https://doi.org/10.1096/fj.202201511R
Erasmus, M. F., Dovner, M., Ferrara, F., D’Angelo, S., Teixeira, A. A.1, Leal-Lopes, C., Spector, L., Hopkins, E., & Bradbury, A. R. M. (2023). Determining the affinities of high-affinity antibodies using KinExA and surface plasmon resonance. mAbs, 15(1), 2291209. https://doi.org/10.1080/19420862.2023.2291209
Jo, M. H., Li, J., Jaumouillé, V., Hao, Y., Coppola, J.1, Yan, J., Waterman, C. M., Springer, T. A.1, & Ha, T. (2022). Single-molecule characterization of subtype-specific β1 integrin mechanics. Nature communications, 13(1), 7471. https://doi.org/10.1038/s41467-022-35173-w 2
Gura, T.1, Acker-Palmer, A., Kolodkin, A., Meijers, R.1, Mizuno, N., Seiradake, E., & Tessier-Lavigne, M. (2022). Molecular neuroscience community shares perspectives. Neuron, 110(22), 3656–3660. https://doi.org/10.1016/j.neuron.2022.10.029
Zhu, S.1, Sridhar, A., Teng, J., Howard, R. J., Lindahl, E., & Hibbs, R. E. (2022). Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities. Nature communications, 13(1), 4582. https://doi.org/10.1038/s41467-022-32212-4
Sui, Y., Li, J., Andersen, H., Zhang, R.1, Prabhu, S. K., Hoang, T., Venzon, D., Cook, A., Brown, R., Teow, E., Velasco, J., Pessaint, L., Moore, I. N., Lagenaur, L., Talton, J., Breed, M. W., Kramer, J., Bock, K. W., Minai, M., Nagata, B. M., … Berzofsky, J. A. (2022). An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant replication in rhesus macaques. PNAS nexus, 1(3), pgac091. https://doi.org/10.1093/pnasnexus/pgac091
Nedozralova, H., Basnet, N.1, Ibiricu, I., Bodakuntla, S., Biertümpfel, C., & Mizuno, N. (2022). In situ cryo-electron tomography reveals local cellular machineries for axon branch development. The Journal of cell biology, 221(4), e202106086. https://doi.org/10.1083/jcb.202106086
Müller, S., Ackloo, S., Al Chawaf, A., Al-Lazikani, B., Antolin, A., Baell, J. B., Beck, H., Beedie, S., Betz, U. A. K., Bezerra, G. A., Brennan, P. E., Brown, D., Brown, P. J., Bullock, A. N., Carter, A. J., Chaikuad, A., Chaineau, M., Ciulli, A., Collins, I., Dreher, J., … Fuchs, S. M.1, … Arrowsmith, C. H. (2021). Target 2035 – update on the quest for a probe for every protein. RSC medicinal chemistry, 13(1), 13–21. https://doi.org/10.1039/d1md00228g
Zhang, J., Xiao, T., Cai, Y., Lavine, C. L., Peng, H., Zhu, H.1, Anand, K.1, Tong, P., Gautam, A., Mayer, M. L., Walsh, R. M., Rits-Volloch, S., Wesemann, D. R., Yang, W.1, Seaman, M. S., Lu, J., & Chen, B. (2021). Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant. bioRxiv : the preprint server for biology, 2021.08.17.456689. https://doi.org/10.1101/2021.08.17.456689
Cai, Y., Zhang, J., Xiao, T., Lavine, C. L., Rawson, S., Peng, H., Zhu, H.1, Anand, K.1, Tong, P., Gautam, A., Lu, S., Sterling, S. M., Walsh, R. M., Jr, Rits-Volloch, S., Lu, J., Wesemann, D. R., Yang, W.1, Seaman, M. S., & Chen, B. (2021). Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variants. Science (New York, N.Y.), 373(6555), 642–648. https://doi.org/10.1126/science.abi9745
1IPI-affiliated researcher
2Study uses IPI antibodies