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Selected publications

Gura T*, Acker-Palmer A, Kolodkin A, Meijers R*, Mizuno N, Seiradake E, Tessier-Lavigne M. Molecular neuroscience community shares perspectivesNeuron, vol. 185 (22), 2022.

Zhu S*, Sridhar A, Teng J, Howard RJ, Lindahl E, Hibbs RE. Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities. Nature Communications, vol. 13 (4582), 2022.

Sui Y, Li J, Andersen H, Zhang R*, Prabhu SK, Hoang T, Venzon D, Cook A, Brown R, Teow E, Velasco J, Pessaint L, Moore IN, Lagenoaur L, Talton J, Breed MW, Kramer J, Bock KW, Minai M, Nagata BM, Choo-Wosoba H, Lewis MG, Wang L, Berzofsky JA. An intranasally administrated SARS-CoV-2 beta variant subunit booster vaccine prevents beta variant replication in rhesus macaques. PNAS Nexus, vol. 1 (3), 2022.

Nedozralova H, Basnet N*, Ibiricu I, Bodakuntla S, Biertümpfel C, Mizuno N. In situ cryo-electron tomography reveals local cellular machineries for axon branch development. Journal of Cell Biology, vol. 221 (4), 2022.

Müller S, Ackloo S, Al Chawaf A, Al-Lazikani B, Antolin A, Baell JB, Beck H, Beedie S, Betz UAK, Bezerra GA, Brennan PE, Brown D, Brown PJ, Bullock AN, Carter AJ, Chaikuad A, Chaineau M, Ciulli A, Collins I, Dreher J, Drewry D, Edfeldt K, Edwards AM, Egner U, Frye SV, Fuchs SM*, Hall MD, Hartung IV, Hillisch A, Hitchcock SH, Homan E, Kannan N, Kiefer JR, Knapp S, Kostic M, Kubicek S, Leach AR, Lindemann S, Marsden BD, Matsui H, Meier JL, Merk D, Michel M, Morgan MR, Mueller-Fahrnow A, Owen DR, Perry BG, Rosenberg SH, Singh Saikatendu K, Schapira M, Scholten C, Sharma S, Simeonov A, Sundström M, Superti-Furga G, Todd MH, Tredup C, Vedadi M, von Delft F, Willson TM, Winter GE, Workmanfg P, Arrowsmith CH. Target 2035 – update on the quest for a probe for every protein. RSC Medicinal Chemistry, vol. 13 (1), 2022.

Zhang J, Xiao T, Cai Y, Lavine C, Peng H, Zhu H*, Anand K*, Tong P, Gautam A, Mayer M, Walsh RM, Rits-Volloch S, Wesemann DR, Yang W*, Seaman MS, Lu J, Chen B. Membrane fusion and immune evasion by the spike protein of SARS-CoV-2 Delta variant. Science, vol. 374 (6573), 2021.

Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, Loftager M, Andersen LM, Bonde AC, Stavenuiter F, Madsen DE, Li X, Holm TL, Ley CD, Thygesen P, Zhu H*, Zhou R, Thorn K, Yang Z, Hermit MB, Bjelke JR, Hansen BG, Hilden I. A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice. Blood, vol. 131 (14), 2021.

Cai Y, Zhang J, Xiao T, Lavine CL, Rawson S, Peng H, Zhu H*Anand K*, Tong P, Gautam A, Lu S, Sterling SM, Walsh RM, Rits-Volloch S, Lu J, Wesemann DR, Yang W*, Seaman MS, Chen B. Structural basis for enhanced infectivity and immune evasion of SARS-CoV-2 variantsScience, vol. 373 (6555), 2021.

Stewart T, Wolfe BE, Fuchs SM*. Defining the role of the polyasparagine repeat domain of the S. cerevisiae transcription factor Azf1p. Plos One, vol. 16 (5), 2021.

Zhang J, Cai Y, Xiao T, Lu J, Peng H, Sterling SM, Walsh RM Jr, Rits-Volloch S, Zhu H*Woosley AN*Yang W*, Sliz P, Chen B. Structural impact on SARS-CoV-2 spike protein by D614G substitutionScience, vol. 372 (6541), 2021.

Adolf-Bryfogle J*Teets FD*Bahl CD*Toward complete rational control over protein structure and function through computational designCurrent Opinion in Structural Biology, vol. 66, 2021.

Kozak S, Bloch Y, De Munck S, Mikula A, Bento I, Savvides SN, Meijers R*Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesisActa Crystallographica, vol. 76 (12), 2020.

Gao M, Mackley IGP, Mesbahi-Vasey S*, Bamonte HA, Struyvenberg SA, Landolt L, Pederson NJ, Williams LI, Bahl CD*, Brooks L 3rd, Amacher JF. Structural characterization and computational analysis of PDZ domains in Monosiga brevicollisProtein Science, vol. 29 (11), 2020.

Stewart T, Exner AE, Patnaik P, Fuchs SM*. Contractions of the C-Terminal Domain of Saccharomyces cerevisiae Rpb1p Are Mediated by Rad5p. Genes, Genomes, Genetics, vol. 10 (7), 2020.

Raposo CJ, McElroy KA, Fuchs SM*. The Epithelial adhesin 1 tandem repeat region mediates protein display through multiple mechanisms. FEMS Yeast Research, vol. 20 (3), 2020.

Anjanappa R, Garcia-Alai M, Kopicki JD, Lockhauserbaumer J, Aboelmagd M, Hinrichs J, Nemtanu IM, Uetrecht C, Zacharias M, Springer S, Meijers R*Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selectionNature Communications, vol. 11 (1314), 2020.

Ford AS*, Weitzner BD, Bahl CD*Integration of the Rosetta suite with the python software stack via reproducible packaging and core programming interfaces for distributed simulation. Protein Science, vol. 29 (1), 2020.

Buchko GW, Pulavarti SVSRK, Ovchinnikov V, Shaw EA, Rettie SA, Myler PJ, Karplus M, Szyperski T, Baker D, Bahl CD*Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptidesProtein Science, vol. 27 (9), 2018.

Lau YK, Baytshtok V, Howard TA, Fiala BM, Johnson JM, Carter LP, Baker D, Lima CD, Bahl CD*. Discovery and engineering of enhanced SUMO protease enzymes. Journal of Biological Chemistry, vol. 293 (34), 2018.

* Institute for Protein Innovation-affiliated researchers 

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