Powering protein science

Antibodies.Research.Education.

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We’re pioneering a new approach to biological discovery.

IPI is an independent nonprofit research institute that captures the curiosity of academic investigation and the technology and scale of industry to accelerate biomedical research and improve human health.

Antibodies

We discover and develop high-quality antibodies and protein reagents to help researchers answer biology’s biggest research questions.

Research

We lead projects and collaborate with scientists working on biological research questions, particularly in fields related to neurobiology.

Education

We share knowledge through courses and events to equip a new generation of protein scientists to meet biology’s future challenges.

The IPI approach

  • Make synthetic, recombinant antibodies to serve unmet needs within research communities.
  • Target multiple protein family members to increase efficiency and further test for cross-reactivity.
  • Deploy yeast display, while innovating new methods and technologies to discover novel tools.
  • Automate lab systems to optimize throughput and quality in protein production.
  • Collaborate with labs globally to ensure our protein tools are directly applicable in researchers’ assays.
Learn more about our platform

News from the lab

Visual map to Axon Guidance, showing interactions between proteins and receptors.

Proteins and receptors involved in axon guidance. IPI figure by Illustrator Anne-Lise Paris (www.in-graphidi.com).
Core concepts

Axon Guidance: Explained

In the late 19th century, neuroscientist Santiago Ramón y Cajal peered through a microscope at the spinal cords of three-day-old chick embryos and drew what looked...

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Graphic with text that says, "IPI receives grant from Chan Zuckerberg Initiative to develop next-generation protein tools for neuroscience research: Funding supports creation and open distribution of critical research tools to accelerate neuroscience discoveries."
Press releases

IPI receives grant from Chan Zuckerberg Initiative to develop next-generation protein tools for neuroscience research

Funding supports creation and open distribution of critical research tools to accelerate neuroscience discoveries Boston, Massachusetts, February 12, 2025 — The Institute for Protein Innovation (IPI),...

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Visual representation of a brain.

Neurexin and neuroligin antibodies can help study synaptic signaling and neural networks. IPI figure.
Science news

IPI targets neurexin with upcoming antibody suite

Snynaptic function involves the interactions of hundreds, maybe thousands, of different proteins. A particular family, called neurexins, has attracted increasing attention because it appears to breed...

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A researcher scrolls through antibody data, surrounded by biological lab supplies.

Research at IPI. IPI photo by Caitlin Faulds.
Core concepts

Epitope tag antibodies, plasmids and data transparency: A Q&A with Mike Walden

In 2024, the Institute for Protein Innovation (IPI) released a set of antibodies targeting nine frequently used epitope tags, including V5, Protein C, DYKDDDDK, Rho, His,...

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Test our antibodies

Gain early access to novel proteins by testing our beta-stage antibodies in your lab.
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Pursue a joint project

IPI welcomes collaborations large and small in an effort to accelerate protein research.
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Use our proteins

Let our growing catalog of antibodies and protein tools power your next discovery.
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