Talk title: “Modulating cell physiology through ligand-receptor engineering”.
Bio: K. Christopher Garcia, Ph.D., is a professor of molecular and cellular physiology and of structural biology at the Stanford University School of Medicine. He is also an investigator in the Howard Hughes Medical Institute.
The Garcia laboratory investigates structural and functional aspects of cell surface receptor recognition and activation in receptor-ligand systems. The lab uses structural information on receptor-ligand complexes to engineer variant proteins and surrogates to manipulate receptor signaling and cellular function, with an eye towards therapeutic applications.
Garcia has founded or co-founded several biotech companies, including Synthekine, Surrozen, 3T Biosciences and ALX Oncology, that are attempting to clinically develop technologies from his lab. He was elected to the National Academy of Sciences in 2012 and the National Academy of Medicine in 2016.