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K. Dane Wittrup, Ph.D.

K. Dane Wittrup, Ph.D., is the Carbon P. Dubbs Professor of Chemical Engineering and Biological Engineering at the Massachusetts Institute of Technology, and the Associate Director of the Koch Institute for Integrative Cancer Research.

Dane obtained his Ph.D. in Chemical Engineering from the California Institute of Technology in 1988 with Prof. James Bailey. Following a year of postdoctoral research at Amgen, he joined the faculty at the University of Illinois in Champaign/Urbana where, from 1989–1999, he rose to J. W. Westwater Professor of Chemical Engineering, Bioengineering, and Biophysics before his move to MIT.

Dane is responsible for most of the recent advances in directed evolution of biopharmaceutical proteins and display of libraries of antibodies and other binding reagents in yeast. His research interests include pretargeted radioimmunotherapy, biological response modification of EGFR, and immunotherapy of cancer via engineered cytokines and vaccines.

Dane’s awards include the Presidential Young Investigator Award of the National Science Foundation (1990–1995), the Allan P. Colburn Award of the American Institute of Chemical Engineers for excellence in publications for an individual under the age of 35 (1998).  He is a Fellow of the American Institute of Medical and Biological Engineers (1999), a Fellow of the American Association for the Advancement of Science (2011), and a Member of the National Academy of Engineering (2011).

In 2007, Dane co-founded Adimab, Inc. with Tillman Gerngross of Dartmouth University, and serves as Chief Scientific Officer. In 2009, he co-founded Eleven Biotherapeutics, and serves on its Scientific Advisory Board.