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Raymond Burgett

IPI Founder in the cover story of Forbes

IPI Founder Timothy Springer just appeared in the cover essay for Forbes. As a COVID…

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New Capabilities in Computational Protein Design Webinar

  The Protein Society's sixth virtual workshop. Protein Society webinars are free of charge. Visit…

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Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis

Structural studies of glycoproteins and their complexes provide critical insights into their roles in normal…

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A Personal Perspective on mental representations, deliberate practice, and what machine learning can do for biology and medicine

  Timothy A. Springer, Ph.D. Latham Family Professor, Department of Biological Chemistry and Molecular Pharmacology,…

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Making Proteins? Cut the Sugar

In the protein world, structure dictates function. That means the three-dimensional topology of a protein…

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Toward complete rational control over protein structure and function through computational design

The grand challenge of protein design is a general method for producing a polypeptide with…

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The Immunoglobulin Superfamily Campaign

As one of its first efforts, IPI launched a campaign to generate antibodies to a…

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Mini-Proteins: the Next Generation Antibiotics

There is more than one way to kill a bacterium. Antibiotics are small molecules that…

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Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis

Identification of the molecular networks that facilitated the evolution of multicellular animals from their unicellular…

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Lab in the Time of COVID

The outbreak of Covid-19 has changed the world and, closer to home, our laboratory: People…

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Making Antibodies, Animal-Free

As an animal lover, I have always paid attention to the methods that scientists have…

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Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection

Major Histocompatibility Complex (MHC) class I molecules selectively bind peptides for presentation to cytotoxic T…

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