IPI Founder in the cover story of Forbes
IPI Founder Timothy Springer just appeared in the cover essay for Forbes. As a COVID…
New Capabilities in Computational Protein Design Webinar
The Protein Society's sixth virtual workshop. Protein Society webinars are free of charge. Visit…
Homogeneously N-glycosylated proteins derived from the GlycoDelete HEK293 cell line enable diffraction-quality crystallogenesis
Structural studies of glycoproteins and their complexes provide critical insights into their roles in normal…
A Personal Perspective on mental representations, deliberate practice, and what machine learning can do for biology and medicine
Timothy A. Springer, Ph.D. Latham Family Professor, Department of Biological Chemistry and Molecular Pharmacology,…
Making Proteins? Cut the Sugar
In the protein world, structure dictates function. That means the three-dimensional topology of a protein…
Toward complete rational control over protein structure and function through computational design
The grand challenge of protein design is a general method for producing a polypeptide with…
The Immunoglobulin Superfamily Campaign
As one of its first efforts, IPI launched a campaign to generate antibodies to a…
Mini-Proteins: the Next Generation Antibiotics
There is more than one way to kill a bacterium. Antibiotics are small molecules that…
Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis
Identification of the molecular networks that facilitated the evolution of multicellular animals from their unicellular…
Lab in the Time of COVID
The outbreak of Covid-19 has changed the world and, closer to home, our laboratory: People…
Making Antibodies, Animal-Free
As an animal lover, I have always paid attention to the methods that scientists have…
Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection
Major Histocompatibility Complex (MHC) class I molecules selectively bind peptides for presentation to cytotoxic T…