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The Institute for Protein Innovation (IPI) is a nonprofit research organization advancing protein science to accelerate research and improve human health. Located on the Harvard Medical School campus in the Boston Longwood Medical Area, IPI uniquely combines the freedom of academia with the high-throughput scaling of industry to take on transformative projects. IPI has built a robust platform that produces well-characterized, synthetic antibodies and other protein tools. We share them with the biomedical community through licensing, collaboration and commercial distribution. The Institute’s deep protein expertise, collaborative spirit and fit-for-purpose antibodies are powering new biomedical and therapeutic discoveries for academic and industrial researchers worldwide.

Job Overview

IPI’s flagship project, the “Antibody Initiative,” aims to create well-characterized, synthetic antibodies against human cell surface receptors and their ligands, particularly those that are traditionally difficult to target. These antibodies may have high therapeutic and diagnostic potential, but will also serve to enable basic biological discovery.

The Antibody Production Scientist will play an essential role in the high-throughput production, characterization and formulation of synthetic antibodies for this Initiative and other key IPI projects. Specifically, the successful candidate will join a dynamic team generating high-quality antibodies and developing new technologies for ensuring antibody stability.

Having completed a doctorate in protein chemistry, or an equivalent field, the successful candidate will bring to the job experience in mammalian expression, purification and reagent-grade preparation of glycoproteins. The candidate will be adept in quality control and process management and reliably provide detailed documentation on experiments completed.

The Scientist will work in close collaboration with the other Antibody Initiative team members and enjoy the opportunity to contribute to a wide array of novel biological discovery projects. As this position is highly collaborative, strong communication skills are needed. The Scientist will engage with outside collaborators, translate their biological questions into novel protein reagents and share these reagents with the larger research community through abstracts, presentations and publications.

Responsibilities and Duties

  • Express, purify, and characterize glycoproteins from mammalian cells
  • Leverage robotics and automation to increase the quality and throughput of antibody production at IPI
  • Supervise research associates and coordinate with other scientists to ensure efficient, high-quality antibody production
  • Actively lead the experimental design and data production for collaborations and scientific publications 
  • Formulate and package antibodies for use by collaborators and customers
  • Participate in meetings and conferences to engage and recruit outside research groups to participate in the Antibody Initiative


  • Ph.D. degree in mammalian protein expression, protein biochemistry or structural biology
  • Well acquainted with best practices in cell culture and reagent production
  • Ability to work in a fast-paced, intellectually challenging environment
  • Enthusiastic team member with a strong commitment to mission and a desire to conduct impactful science
  • Good organizational and documentation skills


  • Medical, dental and vision plans, with premiums paid at 100%
  • Healthcare reimbursement
  • Life Insurance, short- and long-term disability
  • Flexible spending accounts
  • 401(k) plan with 6% match
  • Tuition reimbursement
  • Generous PTO package
  • Educational assistance
  • Commuter and parking reimbursement
  • Career development opportunities

IPI is an independent 501(c)(3) nonprofit research organization and proud to be an equal opportunity employer.

At IPI, we believe that to truly innovate, we need all perspectives, and an inclusive world is built from a supportive environment. Here all applicants will receive equal consideration for employment without discrimination based on race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or other applicable characteristics.

If interested, please email your resume to

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